Profhilo Structura in Marylebone at Dr Joney De Souza Clinic delivers advanced skin remodelling, deep hydration and improved firmness for the face and body. This next-generation treatment strengthens tissue, enhances elasticity and restores youthful structure. Book your consultation today.
Profhilo Structura Treatment Summary
Profhilo Structura is specifically designed for areas of the face that require more lift and volume such as the cheeks, jawline and temples. It not only hydrates and firms, but also addresses more pronounced signs of aging and volume loss. Deep Hydration: Enhances skin moisture levels for a radiant glow.

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.
Profhilo Structura is one of the most advanced treatments available for improving firmness, density and deep structural support in ageing skin. Many patients choose Structura as a proactive approach to maintain skin strength and prevent early signs of laxity, volume loss and tissue weakening before they become more noticeable.
Rather than altering facial features or affecting muscle movement, Profhilo Structura works by delivering a highly concentrated hybrid hyaluronic acid formula into the deeper layers of the skin. This stimulates collagen, elastin and extracellular matrix renewal, helping to rebuild foundational support and improve skin resilience over time. At Dr Joney De Souza Clinic, the focus is always on subtle enhancement, balanced rejuvenation and long term skin health, using advanced techniques to achieve results that look naturally lifted, firmer and effortlessly refreshed.

Profhilo® Structura is one of the most advanced injectable treatments designed to lift, contour, and rejuvenate the facial profile by targeting superficial fat layers. Two treatments spaced 4 weeks apart are designed to lift and contour areas of the face including cheeks, jawline and temple without adding volume to give an exceptionally natural result.
Profhilo® Structura is a clinically proven treatment which helps to restore superficial fat layers of the skin and help combat the signs of ageing thanks to its intense hydrating capabilities. It tackles age-related concerns such as facial hollowing, skin laxity and midface fat loss with 95% of patients noticing lasting enhancements of the mid-face. It can also improve skin texture by nourishing dermal cells which in turn results in radiant and rejuvenated skin. Profhilo® Structura improves the appearance of lines, wrinkles, sagging and crepey skin and effectively lifts and tightens and improves elasticity with results that continue to improve for up to 6 months following the second treatment.
You will be invited for a medical consultation to assess your suitability for Profhilo treatment.
Profhilo Structura can be used on both the face and body. Popular treatment areas include:
Mid-face and cheeks
Jawline
Lower face
Neck
Décolletage
Arms and abdomen
It is ideal for skin that has begun to lose firmness and structure.
Structura is ideal for patients experiencing early to moderate skin laxity, reduced firmness or thinning skin. It is also suitable for those who want a natural approach to improving lift and density without adding volume like traditional fillers.
No. Structura does not work like traditional fillers. Its purpose is to strengthen and remodel the underlying tissue, not to enhance volume or change facial shape. The result is firmer, more elastic skin that looks naturally refreshed.
Most patients require two sessions, spaced four weeks apart.
Some may benefit from a third session depending on skin condition.
Maintenance treatments are usually recommended every 6–9 months.
Early improvements in hydration and texture may be noticeable within days, but the full lifting and firming effects develop gradually over several weeks as collagen and elastin production increases.
Downtime is minimal. You may notice small bumps, redness or swelling at injection points, which typically resolve within a few hours to 24 hours. Normal activities can usually be resumed straight away.
Yes. Structura pairs well with:
Standard Profhilo
Dermal fillers
Microneedling
Energy-based tightening treatments
Mesotherapy
Dr Joney will recommend the best combination for your skin goals.
Most patients tolerate Structura very well. The injections are quick, and a topical anaesthetic can be applied beforehand to ensure comfort.
Results generally last 6–12 months, depending on age, lifestyle, skin condition and ongoing maintenance treatments.
No. Structura enhances the quality and firmness of your skin without changing facial features. The result is a naturally refreshed, subtly lifted appearance that looks like you, only better supported.
Every Profhilo Structura treatment at Dr Joney De Souza Clinic begins with a detailed consultation. During this appointment, Dr Joney will assess your skin’s structure, firmness and areas of early laxity, as well as discuss your personal goals and the improvements you would like to achieve. He will explain how Profhilo Structura works, what kind of lift and support it can provide, and whether combining it with other treatments may enhance your overall results.
Once your personalised plan is agreed, the skin is gently cleansed and a topical anaesthetic may be applied for comfort. Using precise injection techniques, Dr Joney delivers the hybrid hyaluronic acid formulation into targeted points beneath the skin. These deeper injections are designed to strengthen the underlying tissue, stimulate collagen and elastin, and improve firmness without adding volume. The treatment is quick, with minimal discomfort and no significant downtime.
After your Profhilo Structura treatment, you can return to most normal activities straight away. Mild redness, small bumps or swelling at the injection points are common and usually settle within a few hours to 24 hours as the product begins to disperse and integrate with the tissue.
Dr Joney will provide clear aftercare instructions, which may include avoiding strenuous exercise, heat treatments and applying pressure to the treated areas for 24 to 48 hours. As the formulation activates collagen and elastin production, the skin gradually becomes firmer, more elastic and better supported over the following weeks. Results continue to improve after the second session, which is typically performed four weeks later.
With regular maintenance treatments every six to nine months, you will notice lasting improvements in skin density, support and overall resilience, giving you a refreshed, naturally lifted appearance while preserving your own facial features.


All products used are UK-sourced, premium quality and FDA approved. With a focus on excellence, service, and safety, every treatment is tailored to you. If you have any questions around our pricing please give us a call.
All treatments consist of 1 session unless it is a package, which will have multiple sessions based on treatment.
All Pricing is in GBP.
| Area/Treatment | Price with Dr Joney | Price with Associate |
|---|---|---|
Profhilo Structura - Face | 475 | 400 |
Based at 49 Blandford Street in Marylebone, Dr Joney De Souza Skin & Laser Clinic is known for its refined, personalised approach to aesthetic medicine. Under the expert care of Dr Joney, every treatment is tailored to enhance natural beauty and maintain long-term skin health.
Dr Joney will advise you on aftercare, such as avoiding strenuous exercise or massaging the area for 24 hours. Many patients choose to book a review appointment around two weeks later, where any fine-tuning can be carried out if necessary.
Results typically last between three to six months, depending on your individual response and the area treated. With regular maintenance treatments, you’ll notice smoother skin, softer lines, and a fresher, more relaxed appearance that still looks entirely natural.


Our team would love to hear from you. Whether you have questions, need guidance, or simply want to explore your treatment options, we’re here to support you every step of the way. Reach out in whichever way feels easiest